![]() And that makes it impossible to do animal studies to test things out before trying it in human subjects. As far as experts can tell, no animal - besides humans - has a vagina dominated by lactobacillus. When looking at HIV, researchers found that the virus moves more slowly in an acidic environment and, when there’s less inflammation, there are fewer targets for the virus.īut it’s been hard to study the superhero. Scientists have discovered this environment is also correlated with less inflammation. But Mitchell thinks it comes from the fact that this type of bacteria makes lactic acid which keeps the vagina relatively acidic. Nobody really knows how the special power works. Mitchell said the type found in the vagina is totally different and she credits it with “creating this very stable, peaceful, calm environment in the vagina.” It’s called Lactobacillus crispatus and some within the scientific community have nicknamed it the “superhero of the vagina.” It’s not the same lactobacilli in dairy products nor the one found it in the gut. What she wants to see under the microscope is just one type of bacterium dominating. “But in the vagina, it's really that simplicity is better,” said Mitchell. In most parts of the body, like the gut, having a lot of different types of bacteria is a good thing. Every person has trillions of bacteria living on and in their body. The science behind it is all about bacteria. The idea is simple: Take fluid from a happy vagina and put it in an unhappy one. Genga stumbled across Mitchell’s lab, where after years of work and setbacks, Mitchell’s team was experimenting with vaginal fluid transplants. Eventually, she found what she was looking for. She spent the next several hours digging through medical journals to find some hint of hope. ![]() It makes them feel ashamed,” said Mitchell.Īfter years of failed treatments, one Sunday morning, Genga was so fed up with BV that she made herself a cup of tea and sat down at her computer. It makes them feel uncomfortable with intimacy with a partner. “It really strikes at the core of their relationships. It seems to be associated with infertility.Īnd it impacts more than just the individual. It’s linked to the persistence of human papillomavirus and progression to cervical pre-cancer. It's linked to a higher risk of acquiring HIV or other sexually transmitted infections. BV is associated with a host of serious health issues regardless of whether the person experiences any symptoms.īV is linked to preterm birth. And the problem is deeper than the immediate discomfort. Mitchell said her patients often describe antibiotics as temporary relief rather than a treatment. “The fact that there hasn't been a new treatment is infuriating as a health care provider - and as a woman,” said Caroline Mitchell, director of the MGH’s Vulvovaginal Disorders Program. "The fact that there hasn't been a new treatment is infuriating as a health care provider - and as a woman." Caroline Mitchell Yet one month after taking antibiotics, there is a 40 to 60% chance the BV will have come back. The standard medical treatment - antibiotics - has been unchanged for 40 years. Her experience of having BV return just weeks after treatment is common. She’s tried changing her diet, her soap, her feminine products. In Genga’s years-long attempt to get rid of BV, she tried medications, over-the-counter products, and holistic treatments. But for others, there can be discharge, odor and sometimes itching. The experience can be different for different people. ‘Just so uncomfortable’īV happens when the natural bacteria in a vagina get out of balance. After years of delays, the hope is that this study will offer insights that can help the estimated 21 million Americans, from teenagers to middle-aged women, who have BV. This summer Massachusetts General Hospital started performing the first vaginal fluid transplants in the U.S. BV has been linked to serious long-term health issues and yet, for many people, medicine does not have a good treatment. ![]() More than 50% of African American women have the condition. has BV, and the numbers are even higher for certain groups. At any given moment, almost one in three women in the U.S. “I started to not like my own body because it was fighting me all the time,” said Genga, who is from Rhode Island. Another round of antibiotics helped, but only for four weeks. After her gynecologist diagnosed her with bacterial vaginosis - or BV - she took a course of antibiotics and things seemed better. Jade Genga has been grappling with vaginal discomfort and pain for years.Īt first it seemed like just a nuisance. Agnes Bergerat watch as clinical research coordinator Briah Cooley processes a vaginal fluid donor sample to be stored and then given to people with recurrent BV at the Massachusetts General Hospital.
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